Dipartimenti e Centri di ricerca UniSA. Pubblicazioni scientifiche: Recent submissions
Now showing items 1501-1520 of 2563
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Treatment of de novo femoro-popliteal lesions with a new Drug Coated Balloon: early experience of a single Center in the first 50 patients
(2018)Angioplasty with drug-coated balloon (DCB) is an emerging and reliable method for the treatment of femoro-popliteal lesions. We report our experience with the Stellarex™ DCB in the first 50 patients. Methods - From July ... -
Leg fracture associated with synostosis of interosseous membrane during running in a soccer player
(2017)ntroduction - Leg fractures may occur frequently in sport injuries but it is very rare to find this kind of injury associated with interosseous membrane synostosis. This case report describes a unique case of 42 B1.2 ... -
Elective orthopaedic and trauma patients in southern italy are vitamin d deficient. A pilot study.
(2017)Many patients present with Vitamin D (Vit d; 25 (OH) D) deficiency on admission to hospital. The present study evaluated the levels of serum concentration of 25 (OH) D in patients undergoing elective arthroplasty of the ... -
MicroRNs and cardiovascular diseas es: from bench to beside
(2017)MicroRNAs (microRNAs or miRs) are small, noncoding RNAs that control gene expression by binding to and repressing specific mRNA target and have emered as powerful regulators of many biological processes. Understanding ... -
Transcatheter implantable devices to monitoring of elevated left atrial pressures in patients with chronic heart failure
(2017)Elevated left atrial (LA) pressures are associated with poor prognosis in heart failure (HF). Invasive monitoring of LA-pressures and direct mechanical LAdecompression are associated with functional improvement in patients ... -
SiRNA delivery for control of cyclin d1 and e2f1 expression in crohn’s disease
(2017)Evidence in inflammatory bowel diseases (IBD) supports a connection between inflammation and cancer due to the alteration of the cell cycle with loss of control at the G1/S checkpoint. In this study, we analyze the expression ... -
Mean reticolocyte hemoglobin content index plays a key role to identify children who are carriers of β –thalassemia
(2017)Reticulocyte (r) and red blood cell (RBC) indices provide reliable parameters for screening and monitoring iron deficiency anemia (IDA) patients and β-thalassemia trait (BTT) carriers. The aim of this study is to identify ... -
Pilot study on epigenetic response to a mind-body treatment
(2017)In the last years, epigenetics and functional genomics methods to evaluate the genomic effects and mechanisms of mind-body therapies have increasingly grown. DNA microarray technology has been used to show the involvement ... -
Dexmedetomidine: current role in burn ICU
(2017)Dexmedetomidine (DEX) is a relatively recent a2-adrenergic agonist which provides sedation, anxiolysis and analgesia with much less respiratory depression than other sedatives. These characteristics have implemented the ... -
Obesity and obesity related diseases, sugar consumption and bad oral health: a fatal epidemic mixture. The pediatric and odontologist point of view
(2017)Obesity and dental caries are increasingly widespread pathologies. The former is growing so rapidly that the WHO classified its trend as an “epidemic”. Both are triggered by a number of well known common etiologic factors ... -
Larger blood pressure reduction by fixed-dose compared to free dose combination therapy of ace inhibitor and calcium antagonist in hypertensive patients
(2017)The introduction of fixed combination of ACEi+CCB (Fixed) has significantly increased patients compliance and adherence to therapy. At the moment, however, there are no data suggesting the better control of once-daily fixed ... -
Implementing an ict-based polypharmacy management program in Italy
(2017)Although there is evidence of a growing awareness of the problem, no official policy statements or regulatory guidelines on polypharmacy have been released up to date by Italian Health Authorities. Medication review, ... -
Egfr inhibition in a pretreated sacral chordoma: a rolefor erlotinib? Case report and a brief review of literature
(2017)We describe the case of a 69-year old male with an EGFR- positive Imatinib refractory sacral chordoma with synchronous lung metastases, treated with erlotinib, a first- generation EGFR inhibitor. After disease progression ... -
Microvascular blood flow improvement in hyperglycemic obese adult patients by hypocaloric diet
(2016)The present study was aimed to assess the changes in skin microvascular blood flow (SBF) in newly diagnosed hyperglycemic obese subjects, administered with hypocaloric diet. Adult patients were recruited and divided in ... -
67 kDa laminin receptor (67LR) in normal and neoplastic hematopoietic cells: is its targeting a feasible approach?
(2016)The 67 kDa laminin receptor (67LR) is a non-integrin cell surface receptor for laminin (LM) that derives from a 37 kDa precursor (37LRP). 67LR expression is increased in neoplastic cells and correlates with an enhanced ... -
Urokinase type plasminogen activator receptor (uPAR) as a new therapeutic target in cancer
(2016)The urokinase (uPA)-type plasminogen activator receptor (uPAR) is a GPIanchored receptor that focuses urokinase (uPA) proteolytic activity on the cell surface. uPAR also regulates cell adhesion, migration and proliferati ... -
In vitro apoptotic effects of farnesyltransferase blockade in acute myeloid leukemia cells
(2016)Farnesyltransferase inhibitors (FTIs) are a class of oral anti-cancer drugs currently tested in phase I-II clinical trials for treatment of hematological malignancies. The in vitro effects of various FTIs (alpha-hydroxyf ... -
The urokinase/urokinase receptor system in mast cells: effects of its functional interaction with fmlf receptors
(2016)Mast cell and basophils express the high affinity receptor for IgE (FcRI) and are primary effector cells of allergic disorders. The urokinase (uPA)-mediated plasminogen activation system is involved in physiological and ...
